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Invitrogen™ ORAI2 Polyclonal Antibody

Product Code. 12858552
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Quantity:
100 μg
Unit Size:
100µg
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12858552 100 μg 100µg
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Product Code. 12858552 Supplier Invitrogen™ Supplier No. PA520369

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This item is not returnable. View return policy

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-20369 can be used with blocking peptide PEP-0486.

Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ORAI2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ORAI2
Gene Accession No. Q8BH10, Q96SN7
Gene Alias A730041O15Rik; C7orf19; calcium release-activated calcium channel 2; calcium release-activated calcium modulator 2 protein; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; CBCIP2; H_NH0514P08.8; MEM142B; ORAI calcium release-activated calcium modulator 2; ORAI2; PP1729; Protein orai-2; putative protein ORAI2-2; RGD1310213; TMEM142B; Transmembrane protein 142B
Gene Symbols ORAI2
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the carboxy terminus of human ORAI2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 269717, 80228
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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