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Invitrogen™ Opticin Polyclonal Antibody

Description
Immunogen sequence: LPRKERKRRE EQMPREGDSF EVLPLRNDVL NPDNYGEVID LSNYEELTDY GDQLPEVKVT SLAPATSISP Highest antigen sequence indentity to the following orthologs: Mouse - 50%, Rat - 46%.
Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.
Specifications
Specifications
| Antigen | Opticin |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.20 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | OPTC |
| Gene Accession No. | Q9UBM4 |
| Gene Alias | dermatan sulfate proteoglycan 3; dspg3; Oculoglycan; OPT; Optc; optcl; opticin; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047 |
| Gene Symbols | OPTC |
| Show More |
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