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Oprozomib, MedChemExpress

Product Code. 16484988
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Product Code. 16484988

Brand: Medchem Express HY12113

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Description

MedChemExpress Oprozomib (PR-047) is an orally bioavailable and selective peptide epoxyketone proteasome inhibitor with IC50s of 36 and 82 nM for proteasome (β5) and immunoproteasome (LMP7), respectively. Oprozomib (ONX 0912) induces apoptosis in MM cells.

Oprozomib (PR-047) is an orally bioavailable and selective peptide epoxyketone proteasome inhibitor with IC50s of 36 and 82 nM for proteasome (β5) and immunoproteasome (LMP7), respectively. Oprozomib (ONX 0912) induces apoptosis in MM cells.

Specifications

Chemical Name or Material Oprozomib
Physical Form Solid
CAS 935888-69-0
Color White
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C25H32N4O7S
For Use With (Application) Cancer-Kinase/protease
Synonym ONX 0912 PR-047
Solubility Information DMSO : ≥ 50 mg/mL (93.88 mM)
SMILES C[C@]1(OC1)C([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC(C3=CN=C(C)S3)=O)COC)=O)COC)=O)=O
Molecular Weight (g/mol) 532.61
Formula Weight 532.61
Percent Purity 99.5%
Grade Research
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Research purposes only

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