Invitrogen™ OPRK1 Monoclonal Antibody (387310)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561355

Product Code. 30535024

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Specifications

• Antigen: OPRK1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: P41145
• Gene Symbols: OPRK1
• Immunogen: NS0 mouse myeloma cell line transfected with human KOR, Met1-Val380.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: 387310
• Conjugate: Unconjugated
• Gene: OPRK1
• Gene Alias: kappa opioid receptor; kappa-type opioid receptor; KOPR1; KOR; K-OR-1; KOR-1; MSL-1; Opiate receptor, kappa-1; opioid receptor kappa 1; opioid receptor, kappa 1; opioid receptor, kappa 2; OPRK; OPRK1; Oprk2; Ork1; R21; Ror-d
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 4986
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized