Oncrasin 1, Tocris Bioscience™

Product Code	Brand	Quantity
18075582	Tocris Bioscience 3427/10	10 mg
18025982	Tocris Bioscience 3427/50	50 mg

Description

Proapoptotic agent that induces abnormal nuclear aggregation of PKCι and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC50 ≤ 3 μM) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo.

Chemical Identifiers

• CAS: 75629-57-1
• Molecular Weight (g/mol): 269.73
• InChI Key: ZDRQMXCSSAPUMM-UHFFFAOYSA-N
• PubChem CID: 872445
• SMILES: ClC1=CC=C(CN2C=C(C=O)C3=CC=CC=C23)C=C1

• Molecular Formula: C16H12ClNO
• MDL Number: MFCD01051808
• Synonym: oncrasin-1, 1-4-chlorobenzyl-1h-indole-3-carbaldehyde, oncrasin 1, 1-4-chlorophenyl methyl indole-3-carbaldehyde, 1-4-chlorophenyl methyl-1h-indole-3-carboxaldehyde, 1-4-chloro-benzyl-1h-indole-3-carbaldehyde, oncrasin1, cambridge id 5601604, n-4-chlorobenzyl-3-formylindole, oncrasin hplc
• IUPAC Name: 1-[(4-chlorophenyl)methyl]-1H-indole-3-carbaldehyde

Specifications

• CAS: 75629-57-1
• MDL Number: MFCD01051808
• InChI Key: ZDRQMXCSSAPUMM-UHFFFAOYSA-N
• IUPAC Name: 1-[(4-chlorophenyl)methyl]-1H-indole-3-carbaldehyde
• PubChem CID: 872445
• Percent Purity: >98%

• Molecular Formula: C16H12ClNO
• Synonym: oncrasin-1, 1-4-chlorobenzyl-1h-indole-3-carbaldehyde, oncrasin 1, 1-4-chlorophenyl methyl indole-3-carbaldehyde, 1-4-chlorophenyl methyl-1h-indole-3-carboxaldehyde, 1-4-chloro-benzyl-1h-indole-3-carbaldehyde, oncrasin1, cambridge id 5601604, n-4-chlorobenzyl-3-formylindole, oncrasin hplc
• SMILES: ClC1=CC=C(CN2C=C(C=O)C3=CC=CC=C23)C=C1
• Molecular Weight (g/mol): 269.73
• Formula Weight: 269.73
• Chemical Name or Material: Oncrasin 1

Safety and Handling

Recommended Storage : Store at +4°C