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Invitrogen™ OLIG2 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ P21954
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Description
OLIG2 Polyclonal Antibody for Western Blot, IHC, IP
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Specifications
| OLIG2 | |
| Polyclonal | |
| 0.2M tris with 0.1M glycine and no preservative; pH 8 | |
| Q13516, Q9EQW6 | |
| OLIG2 | |
| Recombinant mouse Olig2. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Immunohistochemistry, Immunoprecipitation, Western Blot | |
| Unconjugated | |
| OLIG2 | |
| AI604895; basic domain, helix-loop-helix protein, class B, 1; Basic helix loop helix protein class B1 (bHLHB1); basic helix-loop-helix protein 19 (bHLHe19); bHLH transcription factor; BHLHB1; bHLHe19; Class B basic helix-loop-helix protein 1; class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; Olg-2; OLIG2; olig-2; Oligo2; Oligo2 antibody; oligodendrocyte lineage transcription factor 2; Oligodendrocyte specific bHLH transcription factor 2; oligodendrocyte transcription factor 2; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; Protein kinase C-binding protein 2; Protein kinase C-binding protein 2 (PRKCBP2); Protein kinase C-binding protein RACK17; RACK17; RK17; wu:fc64g09 | |
| Rabbit | |
| Purified | |
| RUO | |
| 10215, 304103, 50913 | |
| Maintain refrigerated at 2°C to 8°C for up to 1 month. For long term storage store at -20°C | |
| Liquid |
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