Invitrogen™ OLIG2 Monoclonal Antibody (1G11)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA515810

Product Code. 12837832

Description

MA5-15810 targets OLIG2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15810 immunogen is purified recombinant fragment of human OLIG2 expressed in E. Coli. MA5-15810 detects OLIG2 which has a predicted molecular weight of approximately 32kDa.

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.

Specifications

• Antigen: OLIG2
• Classification: Monoclonal
• Concentration: Conc. not determined
• Formulation: PBS with 0.03% sodium azide
• Gene Accession No.: Q13516
• Gene Symbols: OLIG2
• Immunogen: Purified recombinant fragment of human OLIG2 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 10215
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 1G11
• Conjugate: Unconjugated
• Gene: OLIG2
• Gene Alias: AI604895; basic domain, helix-loop-helix protein, class B, 1; Basic helix loop helix protein class B1 (bHLHB1); basic helix-loop-helix protein 19 (bHLHe19); bHLH transcription factor; BHLHB1; bHLHe19; Class B basic helix-loop-helix protein 1; class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; Olg-2; OLIG2; olig-2; Oligo2; Oligo2 antibody; oligodendrocyte lineage transcription factor 2; Oligodendrocyte specific bHLH transcription factor 2; oligodendrocyte transcription factor 2; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; Protein kinase C-binding protein 2; Protein kinase C-binding protein 2 (PRKCBP2); Protein kinase C-binding protein RACK17; RACK17; RK17; wu:fc64g09
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1