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Invitrogen™ OLFM4 Polyclonal Antibody
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Product Code. 17298463 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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17298463 100 μL 100µL
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Product Code. 17298463 Supplier Invitrogen™ Supplier No. PA5115687

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total OLFM4.

OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.
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Specifications

Antigen OLFM4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene OLFM4
Gene Accession No. Q3UZZ4, Q6UX06
Gene Alias Antiapoptotic protein GW112; bA209J19.1; GC1; G-CSF-stimulated clone 1 protein; Gm296; Gm913; GW112; hGC-1; hOLfD; olfactomedin 4; olfactomedin-4; OlfD; OLFM4; OLM4; pPD4; PU.1 difference product 4; UNQ362; UNQ362/PRO698
Gene Symbols OLFM4
Host Species Rabbit
Immunogen A synthesized peptide derived from human OLFM4(Accession Q6UX06), corresponding to amino acid residues N253-Y303.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10562, 290409, 380924
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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