Invitrogen™ OLFM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102310

Product Code. 16648784

Description

Antibody detects endogenous levels of total OLFM1.

The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).

Specifications

• Antigen: OLFM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OLFM1
• Gene Alias: 1B426B; AMY; AW742568; D2Sut1e; neuroblastoma protein; neuronal olfactomedin-related ER localized protein; Noe1; Noel; Noel1; Noelin; Noelin 1; Noelin 2; NOELIN1; OlfA; olfactomedin 1; olfactomedin related ER localized protein; olfactomedin-1; OLFM1; Pancortin; pancortin 1; Pancortin 1-4; Pancortin3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10439, 56177, 93667
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O88998, Q62609, Q99784
• Gene Symbols: OLFM1
• Immunogen: A synthesized peptide derived from human OLFM1(Accession Q99784), corresponding to amino acid residues F312-S362.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG