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Invitrogen™ OLFM1 Polyclonal Antibody
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Product Code. 16648784
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Quantity:
100 μL
Unit Size:
100µL
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16648784 100 μL 100µL
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Product Code. 16648784 Supplier Invitrogen™ Supplier No. PA5102310

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total OLFM1.

The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
TRUSTED_SUSTAINABILITY

Specifications

Antigen OLFM1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene OLFM1
Gene Accession No. O88998, Q62609, Q99784
Gene Alias 1B426B; AMY; AW742568; D2Sut1e; neuroblastoma protein; neuronal olfactomedin-related ER localized protein; Noe1; Noel; Noel1; Noelin; Noelin 1; Noelin 2; NOELIN1; OlfA; olfactomedin 1; olfactomedin related ER localized protein; olfactomedin-1; OLFM1; Pancortin; pancortin 1; Pancortin 1-4; Pancortin3
Gene Symbols OLFM1
Host Species Rabbit
Immunogen A synthesized peptide derived from human OLFM1(Accession Q99784), corresponding to amino acid residues F312-S362.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10439, 56177, 93667
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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