missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Custom Products and Services
  4. Custom Enzymes and Inhibitors
  5. Tocris Bioscience™ OF 1

Tocris Bioscience™ OF 1
GREENER_CHOICE

Product Code. 18768476
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 18768476

Brand: Tocris Bioscience™ 5289/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Selective BRPF1B and BRPF2 inhibitor

OF 1 is a selective BRPF1B and BRPF2 bromodomain inhibitor (Kd values are 100 and 500 nM respectively). Exhibits 39-fold selectivity for BRPF1B and BRPF2 over BRD4. Accelerates FRAP recovery at 5 μM in a BRPF2 FRAP assay. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.
TRUSTED_SUSTAINABILITY

Specifications

Purity 98%
Molecular Formula 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1 H-benzimidazol-5-yl)-2-methylbenzenesulfonamide
CAS 919973-83-4
Content And Storage 4°C
Quantity 10 mg
Product Type OF 1
Molecular Weight (g/mol) M.W. (Observed): 440.31
Inhibitors OF 1

For Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.