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Tocris Bioscience™ OF 1
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Product Code. 18768476
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18768476 10 mg 10mg
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Product Code. 18768476 Supplier Tocris Bioscience™ Supplier No. 5289/10

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166.25 GBP valid until 2026-04-30
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Description

Selective BRPF1B and BRPF2 inhibitor

OF 1 is a selective BRPF1B and BRPF2 bromodomain inhibitor (Kd values are 100 and 500 nM respectively). Exhibits 39-fold selectivity for BRPF1B and BRPF2 over BRD4. Accelerates FRAP recovery at 5 μM in a BRPF2 FRAP assay. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.
TRUSTED_SUSTAINABILITY

Specifications

Purity 98%
Molecular Formula 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1 H-benzimidazol-5-yl)-2-methylbenzenesulfonamide
CAS 919973-83-4
Content And Storage 4°C
Quantity 10 mg
Product Type OF 1
Molecular Weight (g/mol) M.W. (Observed): 440.31
Inhibitors OF 1

For Research Use Only

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