OCT4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16808223	Proteintech 11263-1-AP-20UL	20 μL
16898213	Proteintech 11263-1-AP-150UL	150 μL

Description

Oct4 is a maternally expressed octamer-binding protein that was the first transcription factor described for the early stages of development. Oct4 is one of the four Yamaka factors, necessary for embryonic stem cell pluripotency. Pluripotent stem (iPS) cells, can be created by expressing Oct4 and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Oct4, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. A translocation of this gene with the Ewing′s sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation.

Specifications

• Antigen: OCT4
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse, Human
• Gene Accession No.: P20263, Q01860
• Gene ID (Entrez): 18999, 294562, 5460
• Immunogen: OCT4 Fusion Protein Ag1794
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: POU5F1

• Concentration: 0.36 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Oct 3, Oct 4, OCT3, OCT3/4, OCT4, Octamer binding protein 3, Octamer binding protein 4, OTF 3, OTF3, OTF4, POU class 5 homeobox 1, POU5F1
• Gene Symbols: Pou5f1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody