Invitrogen™ OCT1 (POU2F1) Recombinant Rabbit Monoclonal Antibody (13H18L58)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ 702832

Product Code. 16381714

Description

This antibody is predicted to react with Monkey, Bovine, Cat. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Specifications

• Antigen: OCT1 (POU2F1)
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P14859
• Gene Symbols: POU2F1
• Immunogen: Protein corresponding to human OCT-1 [aa1-aa200].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Western Blot, Immunocytochemistry
• Clone: 13H18L58
• Conjugate: Unconjugated
• Gene: POU2F1
• Gene Alias: 2810482H01Rik; NF-A1; OCT1; oct-1; oct-1B; octamer binding protein 1; octamer-binding protein 1; Octamer-binding transcription factor 1; Octamer-binding transcription factor-1; Otf1; OTF-1; POU class 2 homeobox 1; POU domain, class 2, transcription factor 1; Pou2f1; ubiquitous transcription factor
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5451
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid