Invitrogen™ OAS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582113

Product Code. 16399074

Description

Immunogen sequence: VFLSPLTTFQ DQLNRRGEFI QEIRRQLEAC QRERAFSVKF EVQAPRWGNP RALSFVLSSL QLGEGVEFDV LPAFDALGQL TGGYKPNPQI YVKLIEECTD LQKEGEFSTC FTELQRDFLK QRPTKLKSLI RLVKHWYQNC KK Highest antigen sequence indentity to the following orthologs: Mouse - 70%, Rat - 68%.

OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.

Specifications

• Antigen: OAS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OAS1
• Gene Alias: (2-5')oligo(A) synthase 1; (2-5')oligo(A) synthase 1A; (2-5')oligo(A) synthetase 1; (2-5')oligo(A) synthetase 1A; 2',5'-oligo A synthetase 1; 2',5'-oligoadenylate synthetase 1, 40/46kDa; 25 oligoadenylate synthetase; 2'-5' oligoadenylate synthetase; 2'-5' oligoadenylate synthetase 1; 2'-5' oligoadenylate synthetase 1A; 2'-5' oligoadenylate synthetase 1G; 2-5A synthase 1; 2-5A synthase 1A; 2-5A synthetase 1; 2-5A synthetase 1A; 2'-5'-oligoadenylate synthase 1; 2'-5'-oligoadenylate synthase 1; LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 1; 2'-5'-oligoadenylate synthase 1A; 2'-5'-oligoadenylate synthetase 1; 2-5-oligoadenylate synthetase 1; 2'-5'-oligoadenylate synthetase 1, 40/46kDa; 2'-5'-oligoisoadenylate synthetase 1; E16 (2'-5') oligo A synthetase; E18/E16; IFI 4; IFI4; IFI-4; L3; LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 1; OAS 1; Oas1; Oas1a; Oas1g; OIAS; Oias1; OIASI; p42 OAS; p46/p42 OAS
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4938
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P00973
• Gene Symbols: OAS1
• Immunogen: Recombinant protein corresponding to Human OAS1. Recombinant protein control fragment (Product #RP-102253).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG