Invitrogen™ NY-BR-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5101251

Product Code. 16607734

Description

Antibody detects endogenous levels of total AN30A.

NY-BR-1 is a novel differentiation marker predominantly expressed in normal breast and breast cancer. It has been shown by Immunohistochemistry (IHC) that NY-BR-1 was present solely in ductal epithelium of normal breast tissue. Invasive carcinoma of the breast and carcinoma in situ were positive for NY-BR-1, whereas most other tumors and normal tissues are negative, with the exceptions of one-third of sweat gland carcinomas and around two percent of prostate carcinoma. NY-BR-1 is reported to express more frequently in estrogen-positive and lymph node-negative primary carcinomas, and more commonly in grade 1 than in grade 2 or grade 3. In a study by Varga et al (2006) forty-nine percent of lymph node metastasis were shown to be positive.

Specifications

• Antigen: NY-BR-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANKRD30A
• Gene Alias: ANKRD30A; ankyrin repeat domain 30A; ankyrin repeat domain-containing protein 30A; breast cancer antigen NY-BR-1; NY-BR-1; serologically defined breast cancer antigen NY-BR-1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 91074
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9BXX3
• Gene Symbols: ANKRD30A
• Immunogen: A synthesized peptide derived from human ANKRD30A(Accession Q9BXX3), corresponding to amino acid residues H1102-L1152.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG