Invitrogen™ NXPH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA557047

Product Code. 15794941

Description

Immunogen sequence: LFCDSKEVVH ATEGLDWEDK DAPGTLVGNV VHSRIISPLR LFVKQSPVPK PGPMAYADSM ENFWDWLANI TEIQEPLART KR Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 68%.

Neurexophilin-1 (also known as NPH1 or NXPH1), Neurexophilin-2 (also known as NPH2 or NXPH2) and Neurexophilin-3 (also known as NPH3 or NXPH3) are members of the Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I-alpha (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.

Specifications

• Antigen: NXPH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NXPH2
• Gene Alias: neurexophilin 2; Neurexophilin2; neurexophilin-2; NPH2; Nxph2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11249
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95156
• Gene Symbols: NXPH2
• Immunogen: Recombinant protein corresponding to Human NXPH2. Recombinant protein control fragment (Product #RP-96122).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG