Rocaglamide, MedChemExpress

Product Code. 16467748

Brand: Medchem Express HY19356

Description

MedChemExpress Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases.

Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ∼50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia.

Specifications

• Chemical Name or Material: Rocaglamide
• CAS: 84573-16-0
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₂₉H₃₁NO₇
• Quantity: 10 mg
• Synonym: Roc-A
• Solubility Information: DMSO : 100 mg/mL (197.80 mM; Need ultrasonic)
• SMILES: O[C@]12[C@](OC3=CC(OC)=CC(OC)=C32)(C4=CC=C(C=C4)OC)[C@H](C5=CC=CC=C5)[C@H]([C@H]1O)C(N(C)C)=O
• Molecular Weight (g/mol): 505.56
• Formula Weight: 505.56
• Percent Purity: 96.43%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only