NUP88 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16836935	Proteintech 55465-1-AP-20UL	20 μL
16826935	Proteintech 55465-1-AP-150UL	150 μL

Description

This antibody is specific to NUP88.

The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nup88 (nucleoporin 88 kDa) is a 741 amino acid protein that localizes to the nucleus and functions as an essential component of the nuclear pore complex. Expressed ubiquitously, Nup88 is subject to phosphorylation by ATM or ATR and is upregulated in maligt neoplasms and precancerous dysplasias, suggesting a role in tumorigenesis. The gene encoding Nup88 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes.

Specifications

• Antigen: NUP88
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q99567
• Gene ID (Entrez): 4927
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: NUP88

• Concentration: 0.3 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: 88 kDa nucleoporin, nucleoporin 88kDa, Nucleoporin Nup88, NUP88
• Gene Symbols: NUP88
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody