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  6. Invitrogen™ NUP107 Recombinant Rabbit Monoclonal Antibody (K01_1W03)

Invitrogen™ NUP107 Recombinant Rabbit Monoclonal Antibody (K01_1W03)

Product Code. 30827877
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30827310 50 μL
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Product Code. 30827877 Supplier Invitrogen™ Supplier No. MA563736

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Description

Rabbit Recombinant Monoclonal Antibody

NUP107 Recombinant Monoclonal Antibody for Western Blot

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUP107
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1W03
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene NUP107
Gene Accession No. P52590, P57740
Gene Alias 107 kDa nucleoporin; AW541137; BcDNA.LD18761; BcDNA:LD18761; C76801; CG6743; CG6743-PA; Dmel\CG6743; Dmel_CG6743; dmNup107; NPHS11; nuclear pore complex; Nuclear pore complex protein Nup107; Nuclear pore complex protein Nup107-like protein; nucleoporin 107; Nucleoporin 107kD; nucleoporin 107kDa; nucleoporin Nup107; Nup; Nup 107; nup107; Nup107-PA; Nup170; NUP84; p105
Gene Symbols NUP107
Host Species Rabbit
Immunogen A synthetic peptide of human Nup107.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116555, 57122
Target Species Human, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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