Invitrogen™ NUP107 Recombinant Rabbit Monoclonal Antibody (24GB155)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30276040	Invitrogen™ MA557139	100 μL
30275831	Invitrogen™ MA557140	20 μL

Description

NUP107 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.

Specifications

• Antigen: NUP107
• Concentration: 0.5 mg/mL
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P52590, P57740
• Gene ID (Entrez): 116555, 57122
• Immunogen: A synthesized peptide derived from human Nup107 (aa 750-800).
• Product Type: Antibody

• Clone: 24GB155
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Rat
• Gene: NUP107
• Gene Alias: 107 kDa nucleoporin; AW541137; BcDNA.LD18761; BcDNA:LD18761; C76801; CG6743; CG6743-PA; Dmel\CG6743; Dmel_CG6743; dmNup107; NPHS11; nuclear pore complex; Nuclear pore complex protein Nup107; Nuclear pore complex protein Nup107-like protein; nucleoporin 107; Nucleoporin 107kD; nucleoporin 107kDa; nucleoporin Nup107; Nup; Nup 107; nup107; Nup107-PA; Nup170; NUP84; p105
• Gene Symbols: NUP107
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography