Invitrogen™ NUDT5 Monoclonal Antibody (739044)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561664

Product Code. 30535840

Description

Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.

Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.

Specifications

• Antigen: NUDT5
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: Q9UKK9
• Gene Symbols: NUDT5
• Immunogen: E. coli-derived recombinant human ADP-Sugar Pyrophosphatase/NUDT5, Glu2-Phe219.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 739044
• Conjugate: Unconjugated
• Gene: NUDT5
• Gene Alias: 8-oxo-dGDP phosphatase; ADP-sugar pyrophosphatase; HSPC115; Nuclear ATP-synthesis protein NUDIX5; Nucleoside diphosphate-linked moiety X motif 5; nudix (nucleoside diphosphate linked moiety X)-type motif 5; nudix hydrolase 5; nudix motif 5; NUDIX5; nudix-type motif 5; NUDT5; YSA1; YSA1H; YSAH1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 11164
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized