Invitrogen™ NUCB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552551

Product Code. 15750501

Description

Immunogen sequence: MSEVDTNKDR LVTLEEFLKA TEKKEFLEPD SWETLDQQQF FTEEELKEYE NIIALQENEL KKKADELQKQ KEELQRQHDQ LEAQKLEYHQ VIQQMEQKKL QQGIPPSGPA GELKFEPR Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.

Specifications

• Antigen: NUCB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NUCB2
• Gene Alias: AI607786; Calnuc; DNA-binding protein NEFA; epididymis secretory protein Li 109; Gastric cancer antigen Zg4; HEL-S-109; LOW QUALITY PROTEIN: nucleobindin-2; NEFA; nesfatin 1; nesfatin-1; Nucb2; nucleobindin 2; nucleobindin-2; Nucleobindin-2/Nesfatin-1; nucleobindin-2-like protein; nucleobinding 2; p54; prepronefastin; prepronesfatin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4925
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P80303
• Gene Symbols: NUCB2
• Immunogen: Recombinant protein corresponding to Human NUCB2. Recombinant protein control fragment (Product #RP-88817).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG