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Tocris Bioscience™ NS 3763

Selective non-competitive kainate antagonist; selective for GLUK5

Specifications

Purity >98%
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Description

Description

Selective non-competitive kainate receptor antagonist; displays selectivity for GluK1 (formerly GLUK5) subunit-containing receptors (IC50 values are 1.6 and > 30 μM for homomeric GluK1 (formerly GLUK5) and GluK2 (formerly GLUK6) receptors respectively). Has minimal activity at AMPA and NMDA receptors (IC50> 30 μM).

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Specifications

Specifications

>98%
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