Invitrogen™ NRG2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA565487

Product Code. 15928234

Description

Immunogen sequence: HVIRRETETTF SGSHSCSPSH HCSTATPTSS HRHESHTWSL ERSESLTSDS QSGIMLSSVG TSKCNSPACV EARARRAAAY NLEERRRATA PPYHDSVDSL Highest antigen sequence identity to the following orthologs - mouse 94%, rat 94%.

Neuregulin 2 is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcripts encoding distinct isoforms have been described.

Specifications

• Antigen: NRG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NRG2
• Gene Alias: divergent of neuregulin-1; Don1; DON-1; HRG2; neural- and thymus-derived activator for ErbB kinases; neuregulin 2; Neuregulin-2; NRG2; NRG-2; NTAK; NTAK alpha1; NTAK_alpha2a; pro-neuregulin-2, membrane-bound isoform; Pro-NRG2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9542
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.04 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14511
• Gene Symbols: NRG2
• Immunogen: Recombinant Human NRG2. Recombinant protein control fragment (Product #RP-104841).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG