Invitrogen™ NREP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575893

Product Code. 15992415

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.1.

Specifications

• Antigen: NREP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NREP
• Gene Alias: AI325076; C5orf13; D0H4S114; D4S114; Harp; high-altitude regulated protein; neuronal protein 3.1; neuronal regeneration related protein; neuronal regeneration related protein homolog; neuronal regeneration-related protein; Nrep; P311; PRO1873; Protein p311; PTZ17; SEZ17
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 338475, 9315
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q16612, Q80Z34
• Gene Symbols: NREP
• Immunogen: Synthetic peptide corresponding to residues in Human NREP.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG