Invitrogen™ NPL Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5113402

Product Code. 17131264

Description

NPL Polyclonal Antibody for Western Blot, ICC/IF, ELISA

Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.

Specifications

• Antigen: NPL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NPL
• Gene Alias: 0610033B02Rik; C112; C1orf13; dihydrodipicolinate synthetase homolog 1; N-acetylneuraminate lyase; N-acetylneuraminate pyruvate lyase; N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NAL; NALase; Npl; NPL1; Sialate lyase; sialate-pyruvate lyase; Sialic acid aldolase; sialic acid lyase
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 74091, 80896
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q9BXD5, Q9DCJ9
• Gene Symbols: NPL
• Immunogen: Recombinant Human N-acetylneuraminate lyase protein (17-77AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG