missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ CXCL10 Human Matched Antibody Pair

Matched Antibody Pair

Brand:  Invitrogen™ CHC2363

263.34 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Code : 50

Additional Details : Weight : 0.50000kg

Product Code. 10533185

  • £395.00 / Each
Estimated Shipment: 16-04-2024
to see stock.
Add to basket

For Research Use Only. All usage must comply with product instructions.
 

Includes: Antibody Pair Kit contains matched, pre-titred and fully optimized Capture (coating) and Detection Antibodies, 3 vials of Recombinant Standard, Streptavidin-HRP concentrate and technical data sheet.

Requires : Buffer reagents required to complete reaction available separately (Cat. No. CNB0011).

Description

Description

The Human CXCL10 Antibody Pair Kit comes with pre-matched antibody pairs, standards, and streptavidin-HRP to develop your own enzyme linked immunosorbent assays (ELISA) to detect and quantify protein levels of human ICXCL10. Buffer reagents needed to complete the ELISA reaction are sold separate as a Buffer Kit for Antibody Pairs (Catalog No. CNB0011). The Assay Buffer included in this Buffer Kit can be used as a blocking reagent for ELISA plates as well as a diluent for ELISA standards and samples, detection antibody, and HRP conjugate. Principle of the method ELISAs are designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody is coated to the bottom of the wells of a microplate, which is an overnight process. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. A sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.

CXCL10 (C-X-C Motif Chemokine Ligand 10) is a 10 kDa protein and member of the CXC family that acts by binding to CXCR3. Binding of CXCL10 to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. CXCL10 is a pro-inflammatory chemoattractant cytokine that attracts activated T lymphocytes. CXCL10 is constitutively expressed at low levels in lymph organs, and the expression is highly induced by IFN- gamma and to some extent by IL12. It is an important biomarker for diagnosis of many clinical conditions, and it plays an important role in host defense and inflammation. CXCL10 exhibits an angiostatic and an antitumor role that is also involved in Th1 inflammatory diseases, Hashimoto's thyroiditis, Graves' disease and Type 1 diabetes mellitus.

Order Info

Shipping Condition: Wet Ice

Specifications

Specifications

HRP
C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1
10 x 96 Tests
3627
Human
ELISA Kit
P02778
CXCL10
RUO
Capture (coating) Antibody, Detection Antibody, Standard, Streptavidin-HRP
2°C to 8°C
Colorimetric Microplate Reader
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

For Research Use Only. Not for use in diagnostic procedures.