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Invitrogen™ IL-12 p40/p70 Human ELISA Kit

Sandwich ELISA Kit

Brand:  Invitrogen™ KHC0121

Code : 50

Additional Details : Weight : 0.50000kg Transport : UN number : 1789 Chem class : 8 Pack group : III

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Product Code. 10049272

  • £389.00 / 96 tests


Estimated Shipment date
from Supplier 09-04-2020
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For Research Use Only. All usage must comply with product instructions.
 

Description

Description

Interleukin-12 (IL-12) is a heterodimeric 70 kD (p70) cytokine composed of two covalently linked, glycosylated chains, 40kD (p40) and 35-kD (p35). Following protein synthesis, an active heterodimer (p70) and a homoodimer of p40 are formed. IL-12 is mainly produced by monocytes, macrophages, and dendritic cells in response to bacterial products such as lipopolysaccharides (LPS), to intracellular pathogens or upon interaction with activated T cells. IL-12 was originally discovered because of its ability to induce interferon-gamma (IFN-γ) production, cell proliferation, and cytotoxicity mediated by natural killer cells and T cells. It is now established that IL-12 also plays a key role in the development of Th1 responses, leading to IFN-γ and IL-2 production. These cytokines can in turn promote T-cell responses and macrophage activation.
Specifications

Specifications

P29459,P29460
Biotin
3592, 3593
Pre-coated 96 well plate, Standard, Standard Dilution Buffer, Biotinylated Detection Antibody, Streptavidin-HRP, HRP Diluent, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
<2pg/mL
<2 pg/mL
Plasma, 50 μL|Serum, 50 μL|Supernatant, 50 μL
1 hr. 20 min.
Human
3.6%
HRP
Human
7.8-500 pg/mL
Colorimetric
Colorimetric Microplate Reader
ELISA Kit
RUO
50 μL
2°C to 8°C
3 hr.
CLMF,CLMF2,IL-12B,IMD28,IMD29,NKSF,NKSF2,CLMF,IL-12A,NFSK,NKSF1,P35
3.2%
96 Tests
Supernatant
Videos
Documents

For Research Use Only. Not for use in diagnostic procedures.