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Invitrogen™ Novex IL-12 Human ELISA Kit

Quantifies natural and recombinant human IL-12 p35/p40 heterodimer (or IL-12p70)

Brand:  Invitrogen™ KHC0121

Code : 50

Additional Details : Weight : 0.50000kg Transport : UN number : 1789 Chem class : 8 Pack group : III

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Product Code. 10049272

  • £375.00 / 96 tests

Estimated Shipment date
from Supplier 21-11-2019

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For Research Use Only. All usage must comply with product instructions.
 

Description

Description

Interleukin-12 (IL-12) is a heterodimeric 70 kD (p70) cytokine composed of two covalently linked, glycosylated chains, 40kD (p40) and 35-kD (p35). Following protein synthesis, an active heterodimer (p70) and a homoodimer of p40 are formed. IL-12 is mainly produced by monocytes, macrophages, and dendritic cells in response to bacterial products such as lipopolysaccharides (LPS), to intracellular pathogens or upon interaction with activated T cells. IL-12 was originally discovered because of its ability to induce interferon-gamma (IFN-γ) production, cell proliferation, and cytotoxicity mediated by natural killer cells and T cells. It is now established that IL-12 also plays a key role in the development of Th1 responses, leading to IFN-γ and IL-2 production. These cytokines can in turn promote T-cell responses and macrophage activation.
Specifications

Specifications

P29459,P29460
Biotin
3592, 3593
Colorimetric Microplate Reader
ELISA Kit
96 Tests
<2 pg/mL
50μL
2-8°C
3 hr
IL12A, IL12B
3.2%
7.8-500 pg/mL
Colorimetric
Pre-coated plate, standard, detector antibody, Streptavidin-HRP, diluents, wash buffer, chromogen, stop solution, and plate covers.
Pre-coated 96 well plate, Standard, Standard Dilution Buffer, Biotinylated Detection Antibody, Streptavidin-HRP, HRP Diluent, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
<2pg/mL
RUO
Plasma,Serum,Supernatant
Plasma,50 μL|Serum,50 μL|Supernatant,50 μL
1 hr 20 min
Human
3.6%
HRP
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For Research Use Only. Not for use in diagnostic procedures.