Invitrogen™ Nortriptyline Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA175481

Product Code. 11549050

Description

Working Concentration: 5 μg/mL. Sensitivity: 10 ng/mL Nortriptyline produces 45% inhibition in a competitive ELISA employing Tricyclic Antidepressants (TCA) (4) polyclonal antibody.

Nortriptyline Base is a tricyclic antidepressant agent used for short-term treatment of various forms of depression. Nortriptyline blocks the norepinephrine presynaptic receptors, thereby blocking the reuptake of this neurotransmitter and raising the concentration in the synaptic cleft in the CNS. Nortriptyline also binds to alpha-adrenergic, histaminergic and cholinergic receptors. Long-term treatment with nortriptyline produces a downregulation of adrenergic receptors due to the increased stimulation of these receptors. [National Center for Biotechnology Information. PubChem Compound Database; CID=4543].

Specifications

• Antigen: Nortriptyline
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide; pH 7.1
• Host Species: Sheep
• Purification Method: Purified
• Regulatory Status: RUO
• Target Species: Chemical
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA
• Conjugate: Unconjugated
• Gene Alias: Aventyl; C19H21N; Desitriptilina; Desmethylamitriptyline; Noritren; Sensaval
• Immunogen: Nortriptyline-BTG.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Target Molecule: Chemical