Invitrogen™ NOR-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534012

Product Code. 15372671

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Bovine, Dog, Elephant, Panda, Rabbit, Pig, Platypus (100%); Marmoset, Mouse, Rat, Bat, Hamster, Opossum, Turkey, Chicken (94%). For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant.

Specifications

• Antigen: NOR-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NR4A3
• Gene Alias: AI573420; CHN; chondrosarcoma, extraskeletal myxoid, fused to EWS; CSMF; MINOR; mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; neuron-derived orphan receptor 1/2; Nor1; NOR-1; NOR-2; Nr4a3; Nuclear hormone receptor NOR-1; nuclear hormone receptor NOR-1/NOR-2; Nuclear receptor subfamily 4 group A member 3; nuclear receptor subfamily 4, group A, member 3; Orphan nuclear receptor TEC; TEC; TEC receptor; Translocated in extraskeletal chondrosarcoma
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100344785, 100684628, 397479, 528877, 8013
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q92570
• Gene Symbols: NR4A3
• Immunogen: Synthetic 17 amino acid peptide from internal region of human NR4A3.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Canine, Rabbit, Bovine, Pig
• Product Type: Antibody
• Isotype: IgG