Invitrogen™ NOR-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA568825

Product Code. 15887233

Description

This target displays homology in the following species: Cow: 86%; Guinea Pig: 93%; Horse: 93%; Human: 93%; Mouse: 100%; Rabbit: 86%; Rat: 100%.

NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant.

Specifications

• Antigen: NOR-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NR4A3
• Gene Alias: AI573420; CHN; chondrosarcoma, extraskeletal myxoid, fused to EWS; CSMF; MINOR; mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; neuron-derived orphan receptor 1/2; Nor1; NOR-1; NOR-2; Nr4a3; Nuclear hormone receptor NOR-1; nuclear hormone receptor NOR-1/NOR-2; Nuclear receptor subfamily 4 group A member 3; nuclear receptor subfamily 4, group A, member 3; Orphan nuclear receptor TEC; TEC; TEC receptor; Translocated in extraskeletal chondrosarcoma
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18124
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9QZB6
• Gene Symbols: NR4A3
• Immunogen: synthetic peptide corresponding to a region of mouse NOR-1 (aa 551-600).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG