Invitrogen™ NOLA3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA563684

Product Code. 15781452

Description

Immunogen sequence: PDDKYSRHRI TIKKRFKVLM TQQPRPVL Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p.

Specifications

• Antigen: NOLA3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NOP10
• Gene Alias: DKCB1; H/ACA ribonucleoprotein complex subunit 3; homolog of yeast Nop10p; NOLA3; NOP10; NOP10 ribonucleoprotein; NOP10 ribonucleoprotein homolog; NOP10P; nucleolar protein 10; Nucleolar protein family A member 3; nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs); snoRNP protein NOP10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55505
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NPE3
• Gene Symbols: NOP10
• Immunogen: Recombinant protein corresponding to Human NOLA3. Recombinant protein control fragment (Product #RP-99053).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG