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Invitrogen™ Noggin Polyclonal Antibody
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Product Code. 15395511
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
15395511 100 μg 100µg
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Product Code. 15395511 Supplier Invitrogen™ Supplier No. PA534595

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Description

Rabbit Polyclonal Antibody

Not suitable for use with Immunohistochemistry - Free Floating. This antibody is predicted to react with horse, chicken and Xenopus laevis based on sequence homology.

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Noggin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.02% sodium azide; pH 7.4
Gene NOG
Gene Accession No. P97466, Q13253
Gene Alias NOG; Noggin; Noggin precursor; noggin; LOW QUALITY PROTEIN: noggin; SYM1; symphalangism 1 (proximal); SYNS1; SYNS1A
Gene Symbols NOG
Host Species Rabbit
Immunogen Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Noggin.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18121, 9241
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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