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Invitrogen™ Noggin Monoclonal Antibody (A11)
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Product Code. 17827002
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200 μL
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200µL
20µL
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17827002 200 μL 200µL
17684166 20 μL 20µL
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Product Code. 17827002 Supplier Invitrogen™ Supplier No. MA541654

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Mouse Monoclonal Antibody

Noggin Monoclonal Antibody for Western Blot, IHC (P)

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Noggin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone A11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene NOG
Gene Accession No. Q13253, Q62809
Gene Alias NOG; Noggin; Noggin precursor; noggin; LOW QUALITY PROTEIN: noggin; SYM1; symphalangism 1 (proximal); SYNS1; SYNS1A
Gene Symbols NOG
Host Species Mouse
Immunogen Recombinant protein Noggin. The antigen corresponds to amino acid range 28-232 of the target protein.
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25495, 9241
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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