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Invitrogen™ NOD1 Polyclonal Antibody

Product Code. 12839162
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Quantity:
100 μg
Unit Size:
100µg
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12839162 100 μg 100µg
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Product Code. 12839162 Supplier Invitrogen™ Supplier No. PA521015

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Description

Rabbit Polyclonal Antibody

A suggested positive control is EL4 cell lysate. PA5-21015 can be used with blocking peptide PEP-1129.

NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kappa-B. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOD1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NOD1
Gene Accession No. Q8BHB0, Q9Y239
Gene Alias C230079P11; Card4; caspase recruitment domain 4; caspase recruitment domain family, member 4; caspase recruitment domain-containing protein 4; CLR7.1; F830007N14Rik; NLR family, CARD domain containing 1; Nlrc1; Nod1; nucleotide binding oligomerization domain containing 1; nucleotide-binding oligomerization domain containing 1; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; nucleotide-binding oligomerization domain-containing protein 1; RGD1562269
Gene Symbols NOD1
Host Species Rabbit
Immunogen A 16 amino acid peptide near the carboxy end of human NOD1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10392, 107607, 500133
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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