Invitrogen™ NME4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA567250

Product Code. 15999914

Description

Immunogen sequence: MIGHTDSAEAA PGTIRGDFSV HISRNVIHAS DSVEGAQREI QLWFQSSELV SWADGGQHSS IHPA Highest antigen sequence identity to the following orthologs - mouse 88%, rat 88%.

NME4 is a protein kinases, which are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Specifications

• Antigen: NME4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NME4
• Gene Alias: 2610027N22Rik; 2810024O08Rik; 5730493H09Rik; expressed in non-metastatic cells 4, protein; NDK; NDP kinase D; NDP kinase, mitochondrial; NDPKD; NDPK-D; NM23D; NM23H4; nm23-H4; Nm23M4; NM23-M4; NM23-Z4; NME/NM23 nucleoside diphosphate kinase 4; Nme4; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase 4; nucleoside diphosphate kinase D; Nucleoside diphosphate kinase, mitochondrial; Unknown (protein for MGC:134183); zgc:56482
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4833
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O00746
• Gene Symbols: NME4
• Immunogen: Recombinant Human NME4. Recombinant protein control fragment (Product #RP-107888).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG