NMDAR2D Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA539190

Product Code. 15546101

Description

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilon 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

Specifications

• Antigen: NMDAR2D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRIN2D
• Gene Alias: Glutamate receptor ionotropic, NMDA 2D, GluN2D, EB11, Glutamate [NMDA] receptor subunit epsilon-4, N-methyl D-aspartate receptor subtype 2D, Short name=NMDAR2D, Short name=NR2D, GRIN2D, GluN2D, NMDAR2D, NMDAR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14814, 24412, 2906
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O15399, Q03391, Q62645
• Gene Symbols: GRIN2D
• Immunogen: A synthetic peptide derived from the internal region of human GRIN2D
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG