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Invitrogen™ NLRP6 Polyclonal Antibody

Artikelnummer. 12809172
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Quantity:
100 μg
Pakningsstørrelse:
100µg
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12809172 100 μg 100µg
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Artikelnummer. 12809172 Leverandør Invitrogen™ Leverandørnr. PA521022

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Beskrivelse

Rabbit Polyclonal Antibody

A suggested positive control is human heart tissue lysate. PA5-21022 can be used with blocking peptide PEP-1136.

NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kappa-B and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen NLRP6
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NLRP6
Gene Accession No. P59044
Gene Alias AI504961; angiotensin II/vasopressin receptor; angiotensin/vasopressin receptor; AVR; CLR11.4; dual angiotensin II/vasopressin receptor; NACHT, leucine rich repeat and PYD containing 6; NACHT, LRR and PYD domains-containing protein 6; NACHT/LRR/pyrin domain-containing protein 6; NALP6; Navr; Navr/Avr; NLR family pyrin domain containing 6; NLR family, pyrin domain containing 6; Nlrp6; Non-angiotensin-vasopressin receptor; Non-AVR; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6; PAN3; Pypaf5; PYRIN-containing APAF1-like protein 5; PYRIN-containing APAF1-like protein 5-like
Gene Symbols NLRP6
Host Species Rabbit
Immunogen A 16 amino acid peptide near the amino terminus of human NALP6.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171389
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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