Invitrogen™ NLGN4X Monoclonal Antibody (N98/7)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA527585

Product Code. 16312104

Description

1 μg/mL of MA5-27585 was sufficient for detection of Neuroligin 4 in 20 μg of mouse brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 125-130kDa. Does not cross-react with other Neuroligins. This antibody was formerly sold as clone S98-7.

Neuroligin-4, X linked (also known as NLGN4X, NLGN4, Neuroligin-4, and Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic cell-surface neurexins. These interactions bridge together the synaptic cleft and have an essential role in synaptic transmissions between neurons. There are 5 neuroligin genes in humans: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y. Mutations in NLGN3 and NLGN4X are linked to Autism Spectrum Disorders (ASD). The expression of neuroligin-4, X-linked has been reported on human pluripotent stem cells.

Specifications

• Antigen: NLGN4X
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
• Gene Accession No.: B0F2B4
• Gene Symbols: Nlgn4l
• Immunogen: Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin 4. ~45% identity with Neuroligin-1, -2 and -3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: N98/7
• Conjugate: Unconjugated
• Gene: Nlgn4l
• Gene Alias: ASPGX2; AUTSX2; HLNX; HNL4X; HNLX; KIAA1260; MGC22376; neuroligin 4, X-linked; neuroligin 4-like; Neuroligin X; Neuroligin-4, X-linked; NL4; NL-4; NLGN; Nlgn4; Nlgn4l; NLGN4X; UNQ365/PRO701
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100113365
• Content And Storage: -20°C
• Form: Liquid