Invitrogen™ Nkx2.5 Monoclonal Antibody (4B11)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA518671

Product Code. 15578742

Description

Peptide Sequence: MFPSPALTPT PFSVKDILNL EQQQRSLAAA GELSARLEAT LAPSSCMLAA FKPEAYAGPE AAAPGLPELR AELGRAPSPA KCASAFPAAP AFYPRAYSDP DPAKDPRAEK KELCALQKAV ELEKTEADNA *.

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: Nkx2.5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P52952
• Gene Symbols: Nkx2-5
• Immunogen: NKX2-5 (NP_004378, 1 a.a. ~ 130 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: 4B11
• Conjugate: Unconjugated
• Gene: Nkx2-5
• Gene Alias: Cardiac-specific homeobox; cardiac-specific homeobox 1; CHNG5; CSX; CSX1; Drosophila NK2 transcription factor related, locus 5; FLJ52202; FLJ97166; FLJ97195; FLJ97197; FLJ99536; HLHS2; Homeobox protein CSX; homeobox protein NK-2 homolog E; homeobox protein NKX 2-5; homeobox protein Nkx-2.5; NK2 homeobox 5; NK2 transcription factor related locus 5; NK2 transcription factor related, locus 5; NKX 2-5; NKX2.5; Nkx-2.5; Nkx-25; NKX2-5; NKX2E; NKX4-1; rNKx-2.5; tinman; tinman paralog; VSD3
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1482
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid