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Invitrogen™ Nkx2.1 Monoclonal Antibody (CL14523)

Description
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | Nkx2.1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | CL14523 |
| Concentration | 1.0 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | NKX2-1 |
| Gene Accession No. | P43699 |
| Gene Alias | AV026640; BCH; BHC; homeobox protein NK-2 homolog A; Homeobox protein Nkx-2.1; NK-2; NK2 homeobox 1; NK-2 homolog A; NKX2.1; Nkx-2.1; NKX2-1; NKX2A; NMTC1; RNA polymerase I transcription termination factor; T/EBP; TEBP; Thyroid nuclear factor 1; thyroid transcription factor 1; thyroid transcription factor 1 TTF-1 NK-2; thyroid transcription factor 1-like; thyroid-specific enhancer-binding protein; tinman; TITF1; TTF1; TTF-1 |
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