Invitrogen™ NIT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595756

Product Code. 16518601

Description

Immunogen sequence: MLGFITRPPH RFLSLLCPGL RIPQLSVLCA QPRPRAMAIS SSSCELPLVA VCQVTSTPDK QQNFKTCAEL VREAARLGAC LAFLPEAFDF IARDPAETLH LSEPLGGKLL EEYTQLAREC GLWLSLGGFH ERGQDWEQTQ KIYNCHVLLN; Positive Samples: Rat liver; Cellular Location: Cytoplasm, Mitochondrion.

Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.

Specifications

• Antigen: NIT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NIT1
• Gene Alias: AI255805; Deaminated glutathione amidase; dGSH amidase; ESTM30; MGC57670; Nit1; nitrilase 1; nitrilase homolog 1; rCG_20134; W57327
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 289222
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q7TQ94
• Gene Symbols: NIT1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human NIT1 (NP_0011720211).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG