Invitrogen™ NIPSNAP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520500

Product Code. 12818682

Description

A suggested positive control is human brain tissue lysate. PA5-20500 can be used with blocking peptide PEP-0620.

NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.

Specifications

• Antigen: NIPSNAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NIPSNAP1
• Gene Alias: 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1; 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1; 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans); nipsnap homolog 1 (C. elegans); Nipsnap1; Protein NipSnap homolog 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18082, 360971, 8508
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O55125, Q9BPW8
• Gene Symbols: NIPSNAP1
• Immunogen: An 18 amino acid peptide from near the carboxy terminus of human NIPSNAP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG