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Invitrogen™ NIK Polyclonal Antibody

Product Code. 12808092
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Quantity:
100 μg
Unit Size:
100µg
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12808092 100 μg 100µg
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Product Code. 12808092 Supplier Invitrogen™ Supplier No. PA519871

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Description

Rabbit Polyclonal Antibody

A suggested positive control is 293 cell lysate. PA5-19871 can be used with blocking peptide PEP-0007.

MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NIK
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MAP3K14
Gene Accession No. Q99558
Gene Alias aly; alymphoplasia; FTDCR1B; HS; HsNIK; Map3k14; Mitogen-activated protein kinase kinase kinase 14; NF kappa B-inducing kinase; NF-kappa-beta-inducing kinase; Nfkb inducing kinase; NIK; protein kinase; serine/threonine-protein kinase NIK
Gene Symbols MAP3K14
Host Species Rabbit
Immunogen A peptide corresponding to amino acids 931 to 947 of human NIK.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9020
Target Species Human
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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