Nifedipine, 98%, Thermo Scientific™

Product Code	Brand	Quantity
15495109	Thermo Scientific Alfa Aesar J62811.06	5g
15405119	Thermo Scientific Alfa Aesar J62811.14
15415119	Thermo Scientific Alfa Aesar J62811.22	100g

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

Solubility
Soluble in acetone, methylene chloride, chloroform, ethyl acetate, dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.

Notes
Light sensitive. Store in a cool place. Incompatible with strong acids, strong oxidizing agents, caustics, aliphatic amines, amides, diethylamine, potassium hydride and potassium hydroxide.

Chemical Identifiers

• CAS: 21829-25-4
• Molecular Weight (g/mol): 346.34
• InChI Key: HYIMSNHJOBLJNT-UHFFFAOYSA-N
• PubChem CID: 4485
• IUPAC Name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

• Molecular Formula: C17H18N2O6
• MDL Number: MFCD00057326
• Synonym: nifedipine, procardia, adalat, procardia xl, adalat cc, cordipin, corinfar, fenihidine, citilat, oxcord
• ChEBI: CHEBI:7565
• SMILES: COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC

Specifications

• CAS: 21829-25-4
• MDL Number: MFCD00057326
• Synonym: nifedipine, procardia, adalat, procardia xl, adalat cc, cordipin, corinfar, fenihidine, citilat, oxcord
• InChI Key: HYIMSNHJOBLJNT-UHFFFAOYSA-N
• IUPAC Name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• PubChem CID: 4485
• Formula Weight: 346.33
• Chemical Name or Material: Nifedipine

• Molecular Formula: C17H18N2O6
• Merck Index: 14,6528
• Solubility Information: Soluble in acetone,methylene chloride,chloroform,ethyl acetate,dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.
• SMILES: COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
• Molecular Weight (g/mol): 346.34
• ChEBI: CHEBI:7565
• Percent Purity: 98%

Safety and Handling

GHS H Statement
H302
Harmful if swallowed.

P264b-P270-P301+P312-P330-P501c

H302

missing translation for 'einecsNumber' : 244-598-3

missing translation for 'rtecsNumber' : US7975000

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures

Product Identifier

• Nifedipine

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4

Hazard Statement

• H302-Harmful if swallowed.

Precautionary Statement

• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : Nifedipine

RUO – Research Use Only