missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Pyridines and derivatives
  7. Nicotinamide, MedChemExpress

Nicotinamide, MedChemExpress

Product Code. 16492059
Encompass_Preferred
Click to view available options
Quantity:
1 g
5 g
Unit Size:
1g
5g
This item is not returnable. View return policy

Product Code. 16492059

Brand: Medchem Express HYB0150

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Nicotinamide is a form of vitamin B3 or niacin that inhibits sirtuin 2 (SIRT2) activity in vitro, with an EC50 of 2 μM. Nicotinamide inhibits up to 90% melanoma cell number and increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibts tumor growth in vivo and improves survival of melanoma-bearing mice, which can be used for the research of skin cancers such as melanoma.

Nicotinamide is a form of vitamin B3 or niacin that inhibits sirtuin 2 (SIRT2) activity in vitro, with an EC50 of 2 μM. Nicotinamide inhibits up to 90% melanoma cell number and increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibts tumor growth in vivo and improves survival of melanoma-bearing mice, which can be used for the research of skin cancers such as melanoma.

Specifications

Chemical Name or Material Nicotinamide
CAS 98-92-0
Color White
Purity Grade Notes Research
Molecular Formula C6H6N2O
Quantity 1 g
Synonym Niacinamide Nicotinic acid amide
Solubility Information DMSO : 50 mg/mL (409.43 mM; Need ultrasonic) ∣H2O : ≥ 50 mg/mL (409.43 mM)
SMILES O=C(C1=CC=CN=C1)N
Molecular Weight (g/mol) 122.12
Formula Weight 122.12
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.