Invitrogen™ NIBP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA523130

Product Code. 13217428

Description

Immunogen sequence homology: 100% homologous in human (isoform CRA_A and CRA_b), chimpanzee, monkey, mouse, opossum, rat and dog; xenopus (94%). Confocal immunofluorescence: Cells were fixed with 4% paraformaldehyde in PBS for 10 min and then permeabilized with 0.5 % Triton X-100 for 20 min at room temperature (RT). The cells were blocked with PBS containing 10 % BSA and probed with NIBP pAB for 1 hour at RT. After washing with PBS, cells were incubated with Alexa conjugated goat anti-mouse antibodies.

NIBP is a 1246 amino acid intracellular regulatory protein. Reports suggest that NIBP physically interacts with NIK, IKK (beta), but not IKK (alpha) or IKK (gamma) and thus acts as a novel enhancer of cytokine-induced NF-(kappa) B signaling pathway. Due to its neuronal expression NIBP is considered as a potential target for modulating the NF-(kappa) B signaling cascade in neuronal pathologies dependent upon abnormal activation of this pathway. NIBP is mainly expressed in brain, muscle, heart, and kidney.

Specifications

• Antigen: NIBP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRAPPC9
• Gene Alias: 1810044A24Rik; 2900005P22Rik; 4632408O18Rik; hypothetical protein LOC533451; Ibp; IKBKBBP; IKK2 binding protein; Kiaa1882; mKIAA1882; MRT13; Nibp; NIK- and IKBKB-binding protein; NIK and IKK(beta) binding protein; NIK and IKK{beta} binding protein; NIK and IKK-beta binding protein; RGD1309461; T1; trafficking protein particle complex 9; trafficking protein particle complex subunit 9; TRAPP 120 kDa subunit; TRAPPC9; TRS120; TRS130; tularik gene 1 protein
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Canine, Monkey, Bovine, Chicken
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: Whole serum with 50% glycerol and 0.025% sodium azide
• Gene Accession No.: Q32PH0, Q3U0M1, Q96Q05
• Gene Symbols: TRAPPC9
• Immunogen: Synthetic peptide corresponding to amino acids in a range between 30-80 of mouse TLR4.
• Regulatory Status: RUO
• Gene ID (Entrez): 420312, 482058, 533451, 76510, 83696
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid