Invitrogen™ NGFR Monoclonal Antibody (ME20.4)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA120167

Product Code. 11593753

Description

Recommended positive controls: human tongue. This antibody does not cross-react with mouse, rat, or chicken p75 NGF receptors. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.

Specifications

• Antigen: NGFR
• Classification: Monoclonal
• Concentration: 2.8 mg/mL
• Formulation: Ascites with 15mM sodium azide
• Gene Accession No.: P08138
• Gene Symbols: Ngfr
• Immunogen: Human melanoma cell line WM245.
• Regulatory Status: RUO
• Gene ID (Entrez): 100525607, 101101519, 4804
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Inhibition Assays, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization, Radioimmune Assays (RIA), Western Blot
• Clone: ME20.4
• Conjugate: Unconjugated
• Gene: Ngfr
• Gene Alias: CD271; CD271 antigen; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16; low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; NGFR; NGR; p75; p-75; p75 ICD; p75 neurotrophin receptor; p75 ntr; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tnfrsf16; TNR16; Tumor necrosis factor receptor superfamily member 16
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey, Pig, Feline
• Product Type: Antibody
• Isotype: IgG1