Invitrogen™ NGAL Monoclonal Antibody (15)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ ABS0381502

Product Code. 15396281

Description

Specificity: ABS 038-15-02 does not cross-react with NGAL from other mammalian species tested. Reactivity: ABS 038-15-02 binds human NGAL in solution and coated onto a solid phase. ABS 038-15-02 can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibodies HYB 211-02-02, ABS 038-04-02, ABS 038-14-02, ABS 038-23-02 and ABS 038-26-02. Using biotinylated ABS 038-15-02 as a detection antibody, the assay reacts equally with NGAL monomer and homodimer on a mass basis. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.

Specifications

• Antigen: NGAL
• Classification: Monoclonal
• Concentration: 1.05 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P80188
• Gene Symbols: LCN2
• Immunogen: Recombinant human NGAL adsorbed onto aluminum hydroxide gel.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 15
• Conjugate: Unconjugated
• Gene: LCN2
• Gene Alias: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; AW212229; HGNC:6526; HNL; LCN2; lipocalin 2; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin; Siderocalin LCN2; Sip24; SV-40-induced 24P3 protein; uterocalin
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3934
• Content And Storage: 4°C, store in dark
• Form: Liquid